Rejuran Polynucleotides

Rejuran skin boosters are clinically proven to be safe and well tolerated when performed by trained medical professionals. However, as with any injectable treatment, mild side effects can occasionally occur.

You may experience temporary redness, swelling, tenderness, or small bruises at the injection sites — these are completely normal and typically resolve within a few days. In rare cases, more significant reactions such as infection or hypersensitivity may occur, which can be safely managed by your practitioner.

Each formula in the Rejuran range — Rejuran Healer, Rejuran S, Rejuran I, and Rejuran HB — contains biocompatible polynucleotides (PNs) derived from salmon DNA, a substance widely recognised for its safety and regenerative properties.

All Rejuran treatments — including Rejuran Healer, Rejuran S, Rejuran I, and Rejuran HB — work through the regenerative power of polynucleotides (PNs), the building blocks of DNA and RNA. These natural molecules encourage the skin to repair, renew, and restore itself at a cellular level.

When injected into the skin, polynucleotides stimulate cell regeneration, collagen and elastin production, and improved circulation, leading to smoother, firmer, and more radiant skin over time. They also have anti-inflammatory and antioxidant properties, which help calm irritation, reduce redness, and repair damage caused by factors such as sun exposure and pollution.

Each Rejuran formula targets specific concerns:

• Rejuran Healer rejuvenates and strengthens the skin barrier.
• Rejuran S smooths and softens scars.
• Rejuran I restores elasticity and brightness around the eyes.
• Rejuran HB deeply hydrates and improves overall glow.

By improving cell health and supporting collagen renewal, Rejuran delivers naturally radiant, youthful-looking skin.

The results of Rejuran treatments are long-lasting but not permanent. Each formula — Rejuran Healer, Rejuran S, Rejuran I, and Rejuran HB — works by stimulating the skin’s natural ability to regenerate and produce collagen and elastin, gradually improving texture, firmness, and radiance.

• Rejuran Healer helps restore overall skin health and resilience.
• Rejuran S targets scars and uneven texture for smoother skin.
• Rejuran I rejuvenates and brightens the delicate under-eye area.
• Rejuran HB enhances deep hydration and suppleness.

As the body naturally continues to age, these effects will soften over time. To maintain your results, regular maintenance sessions are recommended — typically every few months or as advised by your practitioner.

Rejuran skin boosters are among the most advanced and effective treatments available for skin regeneration and repair. They deliver long-term improvements in texture, tone, and elasticity — all without changing the natural shape or contour of your face.

Each formula within the Rejuran range offers unique benefits:

• Rejuran Healer rejuvenates and strengthens the skin barrier, restoring smoothness and radiance.
• Rejuran S helps reduce the appearance of acne scars and uneven skin texture.
• Rejuran I improves fine lines and dark circles around the eyes for a brighter, well-rested look.
• Rejuran HB delivers deep hydration and enhances glow by combining polynucleotides with hyaluronic acid.

Rejuran treatments can be used on the face, neck, décolletage, and hands, and in some cases, on the scalp to help improve hair quality and density.

All Rejuran treatments — including Rejuran Healer, Rejuran S, Rejuran I, and Rejuran HB — work to naturally regenerate and revitalise the skin from within. They offer a gentle yet effective solution for improving skin quality, structure, and radiance without surgery or significant downtime.

Key benefits include:

• Minimal risk and downtime when performed by qualified professionals
• Suitable for adults aged 18 and over
• Cost-effective alternative to surgical rejuvenation
• Naturally enhanced, long-lasting results
• Little to no discomfort during treatment
• Supports healthy blood circulation and skin repair
• Stimulates collagen and elastin for firmer, smoother skin
• Quick, convenient procedure with visible improvement over time
• Provides results that can last several months or longer, depending on your treatment plan

At our clinic, Rejuran is ideal for anyone seeking refined, natural rejuvenation that restores skin health, luminosity, and youthfulness all year round.

Rejuran HB (Hydro Booster) is a deeply hydrating version of the Rejuran range that combines polynucleotides (PNs) with hyaluronic acid. This dual-action formula both repairs and intensely hydrates the skin, improving its elasticity, texture, and radiance.

While the polynucleotides stimulate collagen regeneration and tissue repair, hyaluronic acid replenishes moisture, leaving the skin smooth, supple, and luminous. Rejuran HB is particularly effective for dry, dull, or tired skin and helps restore a healthy glow from within.

At our clinic, Rejuran HB is a favourite for clients seeking deep hydration and all-over rejuvenation — perfect for maintaining radiant, youthful skin all year round.

Rejuran Healer is the original and most popular treatment in the Rejuran range — designed to rejuvenate and restore the skin at a cellular level. It contains polynucleotides (PNs) derived from salmon DNA, a substance known for its exceptional biocompatibility and regenerative properties.

Once injected, Rejuran Healer encourages the skin to repair and regenerate itself, stimulating new collagen and elastin production while improving hydration and elasticity. This leads to smoother, firmer, and more radiant skin that looks naturally refreshed.

Rejuran Healer is particularly effective for improving fine lines, uneven texture, dullness, and enlarged pores, and is suitable for all skin types and ages. It’s an ideal choice for anyone seeking a gentle, non-surgical treatment to restore skin health and glow all year round.

Rejuran I is a lightweight, delicate formulation from the Rejuran range, created specifically for the eye area. It targets the fine, fragile skin around the eyes, helping to reduce fine lines, improve elasticity, and brighten dark circles.

With a smoother consistency and smaller polynucleotide (PN) molecules than other Rejuran products, Rejuran I is safe for use in sensitive areas such as the under-eyes and crow’s feet. It stimulates collagen and elastin production, strengthens the skin barrier, and enhances overall skin quality without puffiness or heaviness.

Rejuran I is ideal for anyone who wants to refresh tired-looking eyes, smooth fine lines, and restore a youthful, well-rested appearance naturally.

Rejuran S is a specialised treatment within the Rejuran range, formulated to repair and smooth areas of scarring, particularly acne scars and textural irregularities. It contains a higher concentration of polynucleotides (PNs), which promote deep collagen remodelling and accelerate skin healing.

By stimulating cell regeneration and improving skin structure from within, Rejuran S helps to fill and soften depressed scars, enhance overall skin texture, and restore a more even surface.

It’s an excellent choice for those looking to refine and smooth scarred or damaged skin without resorting to aggressive treatments or downtime. At our clinic, Rejuran S is often combined with other regenerative procedures, such as microneedling or laser therapy, for even more transformative results.

Rejuran (PDRN) is an advanced regenerative skin treatment that works by repairing and revitalising the skin from within. It contains polynucleotides (PNs) — naturally derived DNA fragments that help your skin heal, renew, and maintain its youthful structure.

When introduced into the skin, these polynucleotides encourage cell regeneration, boost collagen and elastin production, and strengthen the skin’s barrier. The result is smoother, firmer, and more luminous skin with improved elasticity and resilience.

Beyond general rejuvenation, Rejuran also has anti-inflammatory and antioxidant benefits, making it effective for concerns such as sun damage, acne-prone skin, and early signs of ageing.

At our clinic, we offer the full Rejuran range — Rejuran Healer, Rejuran S, Rejuran I, and Rejuran HB — each formulated to target specific areas and concerns while delivering beautifully natural, healthy-looking results.

Both Rejuran and Profhilo are injectable skin boosters that rejuvenate the skin, but they work in very different ways.

Profhilo contains pure hyaluronic acid, which intensely hydrates the skin and improves elasticity. It spreads evenly under the surface, creating a natural plumping and smoothing effect, making it ideal for those seeking deep hydration and a refreshed glow.

Rejuran, on the other hand, is powered by polynucleotides (PNs) — DNA fragments that repair and regenerate skin cells at a deeper level. Instead of just hydrating, it improves skin structure, collagen production, and overall texture over time. Each version — Rejuran Healer, S, I, and HB — is formulated to target specific concerns such as fine lines, scarring, under-eye rejuvenation, or deep hydration.

In short:

• Profhilo = deep hydration and skin plumping.
• Rejuran = regeneration, repair, and collagen stimulation.

At our clinic, your practitioner will help you decide whether Rejuran, Profhilo, or a combination of both is best suited to your skin goals for a naturally healthy, radiant complexion.

After your Rejuran treatment, it’s normal to experience mild swelling, redness, tenderness, or small bruises at the injection sites. In some cases, you may also notice light spot bleeding where the needle was inserted. These effects are temporary and usually subside within a few days.

To help your skin heal smoothly and reduce the risk of side effects:

• Avoid touching, rubbing, or washing the treated area for at least four hours after your appointment to prevent irritation or infection.
• Refrain from alcohol and spicy foods for at least 48 hours, as these can increase redness or swelling.
• Avoid strenuous exercise, hot showers, saunas, and steam rooms for 48 hours to prevent flushing or further irritation.
• Keep your skin hydrated and use gentle, non-active skincare products for several days.
• Always wear broad-spectrum SPF and limit sun exposure to protect the healing skin.

If you plan to have other aesthetic treatments, speak with your practitioner to determine the best timing for additional procedures.

Should you experience excessive swelling, redness, mottled skin, pain, or fever after treatment, contact our clinic or another qualified healthcare professional immediately. Your safety and comfort are our priority.

Before your Rejuran treatment, it’s important to have a detailed consultation with your practitioner. During this appointment, please share your medical history, including any medications, allergies, or previous reactions to treatments. This helps us determine the most suitable approach for your skin and ensures your treatment is both safe and effective.

If you’re planning other aesthetic procedures — such as injectables, chemical peels, or energy-based treatments — your practitioner will recommend the best treatment schedule to achieve optimal results and minimise the risk of side effects.

To reduce the likelihood of bruising or swelling, avoid alcohol and anti-inflammatory medications such as Ibuprofen for 24–48 hours before your appointment (unless prescribed by your doctor).

At our clinic, your comfort and safety always come first, and your treatment plan will be tailored to deliver beautifully natural results.

While all skin boosters are designed to improve hydration and overall skin quality, Rejuran stands apart due to its unique polynucleotide (PN) technology. Polynucleotides are naturally derived DNA fragments that repair and regenerate skin tissue at a cellular level — rather than simply hydrating or plumping the surface.

This means Rejuran not only improves moisture and glow but also strengthens the skin barrier, enhances elasticity, and promotes long-term collagen renewal. Each formula offers specific benefits:

• Rejuran Healer repairs and revitalises the skin for smoother texture and radiance.
• Rejuran S targets scars and uneven texture with deep collagen stimulation.
• Rejuran I rejuvenates and brightens the delicate eye area.
• Rejuran HB combines polynucleotides with hyaluronic acid for deep hydration and luminosity.

At our clinic, our experienced practitioners will assess your skin concerns and recommend whether Rejuran or another type of skin booster is best suited to achieve your goals naturally and effectively.

At our clinic, we don’t use Rejuran polynucleotides for hair loss. Instead, we offer two highly effective regenerative treatments — Exosomes and Nucleofill Hair — both designed to restore scalp health and support stronger, denser hair growth naturally.

During the treatment, your practitioner will gently deliver the product into the scalp to stimulate cell renewal, improve circulation, and revitalise hair follicles. The procedure is well tolerated with minimal discomfort or downtime.

After treatment, you may experience mild redness or sensitivity in the treated area, which usually settles within a few hours. Over the following weeks, you’ll notice your hair becoming healthier, thicker, and more resilient as the scalp continues to regenerate from within.

Your practitioner will create a personalised treatment plan to help you achieve the best possible long-term results.

At our clinic, we do not use Rejuran polynucleotides for hair restoration. Instead, we offer Exosome therapy and Nucleofill Hair — two cutting-edge treatments designed to improve hair density, strength, and scalp health.

Results develop gradually as the scalp and hair follicles regenerate. Most clients begin to notice early improvements in texture, thickness, and reduced shedding within four to eight weeks, with more visible results appearing over the following months as new hair growth strengthens.

For best results, your practitioner may recommend a course of treatments tailored to your needs, along with an at-home care plan to support long-term scalp and hair vitality.

While polynucleotides can support cell regeneration and improve scalp health, at our clinic we do not use Rejuran for hair growth or density treatments. Instead, we offer more advanced and targeted options — Exosomes and Nucleofill Hair — both specifically formulated to revitalise the scalp and strengthen hair follicles.

These treatments help improve hair density, thickness, and overall scalp condition by stimulating cellular repair and enhancing blood circulation at the root level.

During your consultation, your practitioner will assess your scalp and hair concerns to recommend the most effective solution for achieving stronger, healthier, and fuller-looking hair naturally.

For the best results, Rejuran is usually performed as a course of three sessions minimum, spaced about three to four weeks apart. This allows the polynucleotides to gradually repair and strengthen the skin from within, improving texture, firmness, and overall radiance over time.

Once the initial course is complete, maintenance treatments every six months are recommended to sustain collagen production and keep the skin looking fresh and healthy.

Your practitioner at our clinic will assess your skin and create a personalised treatment plan based on your goals, skin condition, and lifestyle to ensure long-lasting, natural results.

Rejuran can be started from the age of 18 and above, depending on your skin’s needs and your practitioner’s recommendation.

Younger clients often choose Rejuran to maintain skin health, boost collagen, and delay early signs of ageing, while more mature clients use it to restore firmness, smooth texture, and revive overall radiance.

Because Rejuran works by regenerating the skin from within, it’s suitable for adults of all ages who want to improve skin quality naturally — without altering their facial features.

At our clinic, your practitioner will assess your skin and design a tailored Rejuran plan to support your long-term skin goals at any stage of life.

Both Rejuran and ASCE Exosomes are advanced regenerative skin treatments, but they work through different biological mechanisms to improve skin quality.

• Rejuran contains polynucleotides (PNs) — naturally derived DNA fragments that repair and restore the skin at a cellular level. It stimulates collagen and elastin production, strengthens the skin barrier, and improves texture, elasticity, and overall radiance over time.
• ASCE Exosomes, on the other hand, use cell-derived signalling molecules that enhance cellular communication and regeneration. They deliver powerful growth factors and antioxidants that accelerate healing, improve tone and hydration, and calm inflammation.

In essence, Rejuran repairs and rebuilds the skin’s structure, while ASCE Exosomes revitalise and protect it — making them excellent complementary treatments for complete skin regeneration.

At our clinic, your practitioner will assess your skin concerns and recommend whether Rejuran, ASCE Exosomes, or a combination of both will best achieve your desired results.